Curcumin Clinical studies

Clinical Study-5

A review on anti-bacterial, anti-viral, and anti-fungal activity of curcumin

Biomed Res Int. 2014;2014:186864. doi: 10.1155/2014/186864. Epub 2014 Apr 29

Moghadamtousi SZ1, Kadir HA1, Hassandarvish P2, Tajik H3, Abubakar S2, Zandi K4

Abstract

Curcuma longa L. (Zingiberaceae family) and its polyphenolic compound curcumin have been subjected to a variety of antimicrobial investigations due to extensive traditional uses and low side effects. Antimicrobial activities for curcumin and rhizome extract of C. longa against different bacteria, viruses, fungi, and parasites have been reported. The promising results for antimicrobial activity of curcumin made it a good candidate to enhance the inhibitory effect of existing antimicrobial agents through synergism. Different investigations have been done to increase the antimicrobial activity of curcumin, including synthesis of different chemical derivatives to increase its water solubility as well as cell up take of curcumin. This review aims to summarize previous antimicrobial studies of curcumin towards its application in the future studies as a natural antimicrobial agent.

PMID:24877064

PMCID:PMC4022204

DOI:10.1155/2014/186864

[Indexed for MEDLINE]

Database (Oxford). 2015; 2015: bav070.

Published online 2015 Jul 25. doi: 10.1093/database/bav070