Ingredients  of Shimbhala Herbal Extracts – clinical studies/Trials

Clinical study – 8 Apple Cider Vinegar

Influence of apple cider vinegar on blood lipids

J Food Sci Technol. 2016 Mar; 53(3): 1465–1474

Published online 2016 Jan 5

doi:  10.1007/s13197-015-2155-y

PMCID: PMC4984725

1- MScN, BScN. Faculty of Nursing and Midwifery of Amol, Mazandaran University of Medical Sciences, Sari, Iran 2- PhD of Mathematics, Head, Biostatistics Unit, Yong Loo Lin School of Medicine, National University Health System, Singapore



Apple cider vinegar (ACV) has been historically used since centuries to treat many diseases such as hyperlipidemia which is known as a risk factor for atherosclerosis. Early prevention and treatment of atherosclerosis can prevent cardiovascular diseases. Therefore, the present study aimed to review the influence of apple cider vinegar consumption on reducing blood lipid levels. This study(time series design) was carried out on 19 patients with hyperlipidemia. The subjects had been referred to a cardiologist and agreed to consume apple cider vinegar. At baseline, blood samples were obtained to measure cholesterol, triglyceride, low density lipoprotein (LDL) and high density lipoprotein (HDL). The tests were repeated at two, four, and eight weeks of ACV consumption. The results were analyzed using repeated measurement analysis. There were significant reduction in the serum levels of total cholesterol (p < 0.001), triglyceride (p = 0.020), and LDL (p = 0.001) after eight weeks of consuming apple cider vinegar and with an increased HDL levels but the trend was not statistically significant (p = 0.200).

Consumption of apple cider vinegar over a 2 month period had a beneficial effect in drastic reductions in harmful blood lipids and is recommended as a simple and cost-effective treatment for hyperlipidemia.

Reference- [Zahra Beheshti , Yiong Huak Chan, Hamid Sharif Nia, Fatemeh Hajihosseini, Rogheyeh Nazari, Mohammad shaabani, Mohammad Taghi Salehi Omran. Influence of apple cider vinegar on blood lipids. Life Sci J 2012;9(4):2431-2440]. (ISSN: 1097-8135). 360 Keywords: Apple cider vinegar, Hyperlipidemia, Atherosclerosis

The influence of apple cider vinegar has been investigated for hundreds of years.


The results of the present study indicated that 8 weeks of apple cider vinegar consumption significantly reduced harmful lipids, i.e. total cholesterol, LDL, and triglyceride, in blood samples of hyperlipidemic individuals who had never used any lipid-lowering drugs.

Special notes

In a study on rats receiving a high-cholesterol diet, Fushimi et al. observed significant reductions in cholesterol and triglyceride after consuming acetic acid. They reported that the acetic acid of vinegar decreased fatty acid oxidation, inhibited lipogenesis in the liver, and eventually decreased triglyceride and cholesterol levels of concentrations.

Similarly, Mansouri et al. found that consuming apple cider vinegar 6% for one month improved lipid profiles of healthy and diabetic rats.

Setorky et al. detected the benefits of apple cider vinegar consumption on reducing the harmful effects of a high-cholesterol diet, including atherosclerotic lesions in the aorta, among rabbits with hypercholesterolemia. They attributed the results to the influence of components, particularly flavonoids, of apple cider vinegar.Since flavonoids have protective effects against atherosclerosis, their regular consumption will reduce CAD mortality rate among elderly men.


Wholistically, the present study strongly suggests that consumption of apple cider vinegar (ACV) can reduce the LDL, triglyceride, and cholesterol levels in patients with hyperlipidemia. While we know that hyperlipidemia is a major risk factor for atherosclerosis, apple cider vinegar can be used to prevent and even treat this complication and probably other heart problems.